In Vivo Confocal Microscopy (IVCM)
A practical guide to interpreting corneal nerve structure, immune activity, and pathological patterns. Focused on real-world findings such as nerve loss, microneuromas, and inflammation markers.
3. Nerve Density Loss
One of the most important findings in neuropathic corneal pain is reduced nerve density. This can appear as sparse, fragmented, or absent sub-basal nerve fibers.
Nerve loss is often associated with altered sensory processing. However, pain severity does not always correlate with structural loss. Some patients with severe pain show only mild structural abnormalities.