In Vivo Confocal Microscopy (IVCM)
A practical guide to interpreting corneal nerve structure, immune activity, and pathological patterns. Focused on real-world findings such as nerve loss, microneuromas, and inflammation markers.
5. Nerve Tortuosity
Beyond density, nerve shape matters. Abnormal morphology can indicate ongoing pathology.
- Tortuosity: overly twisted or looping nerves
These changes are often associated with metabolic stress, inflammation, or nerve regeneration. They do not always correlate directly with pain severity but indicate altered nerve physiology.